Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681258 | 1.00 | THRB (0.33) | THRBTRPV1TRPA1LTA4H | |
| SCHEMBL29809860 | 1.00 | THRB (0.33) | THRBTRPV1TRPA1LTA4H | |
| SCHEMBL9419874 | 1.00 | THRB (0.33) | THRBTRPV1TRPA1LTA4H | |
| SCHEMBL9419872 | 1.00 | THRB (0.33) | THRBTRPV1TRPA1LTA4H | |
| SCHEMBL16431880 | 0.84 | GABRR1 (0.31) | TRPV1TRPA1LTA4H | |
| SCHEMBL16431878 | 0.84 | GABRR1 (0.31) | TRPV1TRPA1LTA4H | |
| SCHEMBL5868604 | 0.76 | THRB (0.42) | THRB | |
| SCHEMBL5868601 | 0.76 | THRB (0.42) | THRB | |
| SCHEMBL17063554 | 0.74 | THRB (0.40) | THRBTRPV1TRPA1LTA4H | |
| SCHEMBL9679401 | 0.72 | THRB (0.39) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469480-A2 | Process for stereoselective preparation of 5-substituted delta-lactones and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-05 | — | — | EP | disclosed |