Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782546 | 0.83 | THRB (0.46) | THRBTRPA1GPR84 | |
| SCHEMBL16690276 | 0.83 | THRB (0.46) | THRBTRPA1GPR84 | |
| SCHEMBL15689681 | 0.77 | PTPN1 (0.45) | TRPA1CAMK2ATRPV1PTPN1GPR84 | |
| SCHEMBL6066567 | 0.74 | CAMK2A (0.40) | CAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL1399301 | 0.74 | CAMK2A (0.40) | CAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL27768581 | 0.74 | THRB (0.42) | THRB | |
| SCHEMBL9419872 | 0.74 | THRB (0.33) | THRBTRPA1TRPV1LTA4H | |
| SCHEMBL9681252 | 0.74 | THRB (0.33) | THRBTRPA1TRPV1LTA4H | |
| SCHEMBL9681258 | 0.74 | THRB (0.33) | THRBTRPA1TRPV1LTA4H | |
| SCHEMBL29809860 | 0.74 | THRB (0.33) | THRBTRPA1TRPV1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234953-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS LIMITED (GB) | 2022-02-01 | — | — | US | disclosed |
| US-20200215016-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | TDELTAS (GB) | 2020-07-09 | — | — | US | disclosed |
| US-10478415-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS LIMITED (GB) | 2019-11-19 | — | — | US | disclosed |
| US-20170196827-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | TDELTAS (GB) | 2017-07-13 | — | — | US | disclosed |
| US-9579302-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | TDELTAS (GB) | 2017-02-28 | — | — | US | disclosed |
| US-20150250755-A1 | KETONE BODIES TO PROTECT TISSUES FROM DAMAGE BY IONIZING RADIATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (US) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11234953-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | ACACB, BCKDK, ACACA | THRB 318/4885TRPA1 4197/4885CAMK2A 1773/4885 |
| US-10478415-B2 | Ketone bodies to protect tissues from damage by ionizing radiation | ACACB, BCKDK, ACACA | THRB 318/4885TRPA1 4197/4885CAMK2A 1773/4885 |
| US-20150250755-A1 | KETONE BODIES TO PROTECT TISSUES FROM DAMAGE BY IONIZING RADIATION | ACACB, BCKDK, ACACA | THRB 318/4885TRPA1 4197/4885CAMK2A 1773/4885 |
| US-20170196827-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | ACACB, BCKDK, ACACA | THRB 318/4885TRPA1 4197/4885CAMK2A 1773/4885 |
| US-20200215016-A1 | Ketone Bodies To Protect Tissues From Damage By Ionizing Radiation | ACACB, BCKDK, ACACA | THRB 318/4885TRPA1 4197/4885CAMK2A 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.