Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933663 | 0.99 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11728026 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11725862 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11731676 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11728360 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL11729050 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTDDB1 | |
| SCHEMBL11777675 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTDDB1CRBN | |
| SCHEMBL9845601 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL11730202 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11728882 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHDAC4DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | claimed |
| EP-0312762-A1 | Method of safening fungicidal compositions thereof | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| US-4017299-A | Phthalimide derivatives as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| US-5102447-A | Applying 1-(3-chlorophthalimido)cyclohexanecarboxamide to the roots, seeds, leaves or soil surrounding crops to prevent phytotoxic effects of terbufos | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0312762-A1 | Method of safening fungicidal compositions thereof | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |