Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728360 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL11611884 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL29885176 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL11777675 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL5933663 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL11729050 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL11610721 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL28664942 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL9682755 | 0.82 | CA9 (0.42) | ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL9682128 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017299-A | Phthalimide derivatives as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| EP-0427907-A2 | Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4125727-A | Method of preparing imidazoisoindolediones | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4110103-A | Dihydroimidazoisoindolediones and the use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4093441-A | IMIDAZO ISOINDOLEDIONES AND OPTICALOR STEREO ISOMERS THEREOF | AMERICAN CYANAMID COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4092147-A | DIHYDROIMIAZO-ISOINDOLEDIONES | AMERICAN CYANAMID COMPANY (US) | 1978-05-30 | — | — | US | disclosed |
| US-4090860-A | DIHYDROIMIDAZOISOINDOLEDIONE | AMERICAN CYANAMID COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067718-A | IMIDAZO-ISOINDOLEDIONES OR THEIR DIHYDRO DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-4062671-A | Imidazoisoindolediones, and the use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4041045-A | Dihydroimidaz oisoindolediones and the use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-4017510-A | ENANTIOMORPHS | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |