Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888453 | 0.91 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL9681338 | 0.90 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL10889434 | 0.85 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL10885469 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL2319695 | 0.81 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL10886342 | 0.81 | THRB (0.39) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL727028 | 0.79 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL10891993 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL9681207 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A | |
| SCHEMBL10885003 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPK1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |