Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.33 |
| ▸ | TSHR | P16473 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846206 | 0.84 | PDE3B (0.40) | HCAR2HSD17B10KDM4ETSHRALDH1A1 | |
| SCHEMBL9681299 | 0.82 | MAPT (0.35) | HCAR2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL9272505 | 0.78 | PDE4A (0.40) | KDM4ETSHRALDH1A1MAPTPOLB | |
| SCHEMBL9681421 | 0.75 | MAPT (0.37) | HCAR2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL9432058 | 0.72 | TAAR1 (0.50) | CYP1A2 | |
| SCHEMBL9846283 | 0.71 | MAPT (0.35) | HSD17B10KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL9432009 | 0.69 | CD274 (0.38) | KDM4EPDE10APOLB | |
| SCHEMBL9846217 | 0.68 | PDE3B (0.37) | HCAR2KDM4EALDH1A1PDE3BPDE3A | |
| SCHEMBL9432036 | 0.67 | GAA (0.36) | ALDH1A1ALOX15POLB | |
| SCHEMBL9246249 | 0.67 | MAPT (0.32) | KDM4EPDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |