SCHEMBL9681393

SCHEMBL9681393

Cc1cc(Br)c(Br)c(Br)c1C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
APEX1 P27695 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
ALDH1A1 P00352 1/20 0.33
AKR1B1 P15121 1/20 0.32
CA1 P00915 1/20 0.32
CA6 P23280 1/20 0.32
NQO2 P16083 1/20 0.31
TSHR P16473 1/20 0.31
AHR P35869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21218762 0.82 APEX1 (0.38) CYP1A2APEX1TDP1MAPTNPSR1
SCHEMBL21218768 0.82 CYP1A2 (0.46) CYP1A2APEX1ALDH1A1TSHR
SCHEMBL180492 0.79 TDP1 (0.43) APEX1TDP1MAPTNPSR1CA2
SCHEMBL29822788 0.79 TDP1 (0.43) APEX1TDP1MAPTNPSR1CA2
SCHEMBL21218742 0.79 CYP1A2 (0.43) CYP1A2TSHR
SCHEMBL2266180 0.79 CA2 (0.40) APEX1TDP1MAPTNPSR1CA2
SCHEMBL1793576 0.78 CYP1A2 (0.52) CYP1A2APEX1NPSR1ALDH1A1TSHR
SCHEMBL1004500 0.77 ALDH1A1 (0.33) CYP1A2APEX1ALDH1A1TSHR
SCHEMBL9376593 0.77 APEX1 (0.38) CYP1A2APEX1TDP1MAPTNPSR1
SCHEMBL1876935 0.76 CA1 (0.50) CYP1A2APEX1TDP1MAPTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56139546-A None JP disclosed
EP-0475605-A2 Phenolic resin and method for preparing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-03-18 EP disclosed
JP-S56139546-A FLAME-RETARDANT POLYOLEFIN COMPOSITION TOKUYAMA SODA CO LTD 1981-10-31 JP disclosed
US-3932542-A HYDRATED IRON CONTAINING CATALYST GREAT LAKES CHEMICAL CORPORATION (US) 1976-01-13 US disclosed