Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701292 | 0.85 | MAPT (0.74) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL9682931 | 0.83 | MAPT (0.58) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL9683008 | 0.83 | MAPT (0.67) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL9683146 | 0.82 | MAPT (0.57) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL12658349 | 0.80 | MAPT (0.53) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL10508498 | 0.80 | MAPT (0.67) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL9687209 | 0.79 | MAPT (0.53) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL9683160 | 0.78 | MAPT (0.54) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL23652890 | 0.77 | MAPT (0.48) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL14858791 | 0.77 | MAPT (0.44) | MAPTTDP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |