Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688910 | 0.91 | HTR6 (0.53) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL14376796 | 0.90 | MAPT (0.61) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL2879386 | 0.87 | MAPT (0.60) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL5361493 | 0.86 | MAPT (0.70) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL9687736 | 0.85 | SMN1; SMN2 (0.60) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9683146 | 0.84 | MAPT (0.57) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL12004226 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2ALMNAHCAR3 | |
| SCHEMBL4537985 | 0.83 | MAPT (0.62) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL16713330 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL15687598 | 0.83 | POLB (0.61) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |