Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 7/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | EED | O75530 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MLNR | O43193 | 1/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | HLA-A | P04439 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11271737 | 0.98 | SSTR5 (0.68) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL9682069 | 0.93 | SSTR5 (0.65) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL10529762 | 0.91 | SSTR5 (0.78) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL9629504 | 0.88 | SSTR5 (0.59) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL11381151 | 0.87 | SSTR5 (0.88) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL14098264 | 0.86 | KCNH2 (0.53) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL9631290 | 0.84 | SSTR5 (0.72) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL11265895 | 0.84 | KCNH2 (0.83) | SSTR5KCNH2NR4A2EEDCYP1A2 | |
| SCHEMBL11473098 | 0.84 | SSTR5 (0.52) | SSTR5KCNH2EEDCYP1A2CYP2C19 | |
| SCHEMBL11279705 | 0.84 | SSTR5 (0.66) | SSTR5KCNH2NR4A2EEDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106857-A | N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-21 | — | — | US | claimed |
| US-5106857-A | N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |