Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.49 |
| ▸ | EED | O75530 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14098264 | 0.92 | KCNH2 (0.53) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL9679915 | 0.88 | KCNH2 (0.54) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL9682069 | 0.87 | SSTR5 (0.65) | ALDH1A1SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL14228047 | 0.85 | SSTR5 (0.58) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL9631290 | 0.83 | SSTR5 (0.72) | ALDH1A1SMN1; SMN2LMNAMAPTKCNH2 | |
| SCHEMBL14173608 | 0.82 | KCNH2 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTKCNH2 | |
| SCHEMBL20715332 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL13958840 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL9681405 | 0.79 | SSTR5 (0.71) | ALDH1A1SMN1; SMN2LMNAMAPTL3MBTL1 | |
| Oxalic Acid SCHEMBL9630418 | 0.78 | SSTR5 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106857-A | N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-21 | — | — | US | claimed |
| US-5106857-A | N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |