Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029899 | 0.86 | RIPK1 (0.43) | SLC6A4RIPK1SLC6A3SLC6A2ATM | |
| SCHEMBL19117766 | 0.78 | TSHR (0.52) | SLC6A4SLC6A3SLC6A2KDM4ECHRM2 | |
| SCHEMBL409949 | 0.78 | TSHR (0.52) | SLC6A4SLC6A3SLC6A2KDM4ECHRM2 | |
| SCHEMBL30288156 | 0.78 | ESR1 (0.52) | SLC6A3SLC6A2CHRM2CHRM1ADRA1A | |
| SCHEMBL12084095 | 0.75 | ACP3 (0.51) | SLC6A4SLC6A3SLC6A2PDPK1KDM4E | |
| SCHEMBL14160147 | 0.75 | ESR1 (0.44) | SLC6A4PDPK1KDM4ETAAR1 | |
| SCHEMBL30265787 | 0.74 | ATM (0.38) | SLC6A4RIPK1SLC6A3SLC6A2ATM | |
| SCHEMBL28944521 | 0.74 | RIPK1 (0.35) | SLC6A4RIPK1SLC6A3SLC6A2ATM | |
| SCHEMBL21029362 | 0.74 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2PDPK1ATM | |
| SCHEMBL9440541 | 0.74 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2PDPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488602-A1 | Aryl derivatives | ZENECA LIMITED (GB) | 1992-06-03 | — | — | EP | disclosed |