Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682068 | 0.80 | GRIN2D (0.41) | DDB1CRBNKMT2ACYP1A2CYP2C19 | |
| SCHEMBL4057756 | 0.73 | LMNA (0.44) | KMT2AGAAALDH1A1MEN1LMNA | |
| SCHEMBL28270390 | 0.70 | HRH1 (0.44) | KMT2ACYP1A2CYP2C19GAALMNA | |
| SCHEMBL8283151 | 0.69 | GAA (0.50) | KMT2ACYP1A2CYP2C19GAAALDH1A1 | |
| SCHEMBL28993648 | 0.68 | HRH1 (0.42) | KMT2ACYP1A2CYP2C19GAALMNA | |
| SCHEMBL17033077 | 0.67 | HRH3 (0.44) | GAAALDH1A1LMNAALOX15POLB | |
| SCHEMBL7915833 | 0.67 | MAOA (0.50) | GAALMNAHRH1 | |
| SCHEMBL29452029 | 0.67 | MAOA (0.50) | GAALMNAHRH1 | |
| SCHEMBL8050429 | 0.67 | GAA (0.40) | KMT2ACYP1A2CYP2C19GAAALDH1A1 | |
| SCHEMBL27053801 | 0.66 | LMNA (0.60) | GAALMNARAB9APOLBHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118697-A | Acyl-coenzyme A: cholesterol acyltransferase inhibitors for reducing blood cholesterol levels | WARNER-LAMBERT COMPANY (US) | 1992-06-02 | — | — | US | disclosed |