Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681588 | 1.00 | FAAH (0.54) | FAAHITGB3ITGA2BEPHX2HDAC3 | |
| SCHEMBL21541233 | 0.86 | HDAC1 (0.57) | HDAC1HDAC6 | |
| SCHEMBL30831414 | 0.84 | FAAH (0.56) | FAAHITGB3ITGA2BEPHX2CTSG | |
| SCHEMBL8750017 | 0.83 | FAAH (0.70) | FAAHEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL9220936 | 0.83 | FAAH (0.65) | FAAHITGB3ITGA2BEPHX2HDAC3 | |
| SCHEMBL9220945 | 0.83 | FAAH (0.65) | FAAHITGB3ITGA2BEPHX2HDAC3 | |
| SCHEMBL30737274 | 0.83 | GPR34 (0.47) | ITGB3ITGA2BACE | |
| SCHEMBL9223275 | 0.82 | FAAH (0.57) | FAAHITGB3ITGA2BEPHX2HDAC3 | |
| SCHEMBL2806565 | 0.82 | FAAH (0.67) | FAAHEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL2806570 | 0.82 | FAAH (0.67) | FAAHEPHX2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | disclosed |