Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458798 | 0.86 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL10458525 | 0.86 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL23805897 | 0.83 | SRD5A2 (0.52) | SMN1; SMN2ALDH1A1TSHRMAPK1MAOA | |
| SCHEMBL10456875 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL22355416 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL12205867 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL10717258 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL9680429 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL9679495 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TSHRMAPK1NAMPT | |
| SCHEMBL10943297 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TSHRMAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |