Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456875 | 0.87 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9681596 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9679431 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10458525 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9681072 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9681331 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL3667774 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL22355416 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL9681170 | 0.81 | TDP1 (0.59) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 | |
| SCHEMBL10886205 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900823-A | PHOTOINITIATORS FOR PHOTOCURING | CIBA-GEIGY CORPORATION (US) | 1990-02-13 | — | — | US | disclosed |
| US-4739052-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4559371-A | FOR PRINTING INKS AND PAINTS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0117233-A1 | Coloured photo-curable mouldings | CIBA-GEIGY AG (CH) | 1984-08-29 | — | — | EP | disclosed |