Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681606 | 0.86 | GSK3B (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10384862 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTALOX12SMN1; SMN2KMT2A | |
| SCHEMBL10385927 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTUSP2ALOX12HPGD | |
| SCHEMBL9679954 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10384867 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10979628 | 0.83 | LMNA (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL8898956 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTUSP2ALOX12HPGD | |
| SCHEMBL8897354 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTUSP2ALOX12HPGD | |
| SCHEMBL8898761 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTUSP2HPGDSMN1; SMN2 | |
| SCHEMBL275396 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTUSP2ALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |