Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 7/20 | 0.79 |
| ▸ | CDC42 | P60953 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679427 | 0.93 | RAC1 (0.69) | RAC1CDC42MAPTALDH1A1HPGD | |
| SCHEMBL9679413 | 0.93 | RAC1 (0.69) | RAC1CDC42MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8709205 | 0.92 | RAC1 (0.70) | RAC1CDC42MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8709312 | 0.92 | RAC1 (0.70) | RAC1CDC42MAPTALDH1A1HPGD | |
| SCHEMBL13334193 | 0.88 | RAC1 (1.00) | RAC1CDC42MAPTALDH1A1HPGD | |
| SCHEMBL8712325 | 0.87 | RAC1 (0.61) | RAC1CDC42MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3321466 | 0.87 | RAC1 (1.00) | RAC1CDC42MAPTALDH1A1HPGD | |
| SCHEMBL13334159 | 0.84 | RAC1 (1.00) | RAC1CDC42MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3320523 | 0.83 | RAC1 (1.00) | RAC1CDC42MAPTALDH1A1HPGD | |
| Fagaridine SCHEMBL29369428 | 0.83 | ALDH1A1 (0.77) | RAC1CDC42MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487930-A1 | Process for preparing benzo[C]phenanthridinium derivatives, and novel compounds prepared by said process | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-06-03 | — | — | EP | disclosed |