Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627293 | 0.96 | FAAH (0.47) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL2381597 | 0.88 | MGAM (0.46) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL2728978 | 0.82 | FAAH (0.58) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL9680472 | 0.82 | MGAM (0.41) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL28041885 | 0.81 | FAAH (0.49) | FAAHCNR1CNR2ZDHHC7LMNA | |
| SCHEMBL3376679 | 0.81 | CTSK (0.49) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL29133861 | 0.81 | FAAH (0.66) | FAAHCNR1CNR2MGAMGAA | |
| SCHEMBL22366198 | 0.79 | FAAH (0.69) | FAAHCNR1CNR2ZDHHC7LMNA | |
| SCHEMBL28322944 | 0.79 | FAAH (0.69) | FAAHCNR1CNR2ZDHHC7LMNA | |
| SCHEMBL3281994 | 0.79 | FAAH (0.44) | FAAHCNR1CNR2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126373-A | Ester or diester of 1,3-butanediol or 1,3-pentanediol; side effect reduction | BRUNENGRABER HENRI (US) | 1992-06-30 | — | — | US | disclosed |