Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683313 | 0.94 | TBXA2R (0.64) | TBXA2RAGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9683131 | 0.93 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9682437 | 0.92 | TBXA2R (0.76) | TBXA2RAGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9683508 | 0.92 | TBXA2R (0.62) | TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL9681897 | 0.91 | TBXA2R (0.78) | TBXA2RMEN1KMT2ALMNATP53 | |
| SCHEMBL9681443 | 0.89 | TBXA2R (0.61) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9683048 | 0.88 | MAPT (0.53) | TBXA2RPOLBMEN1KMT2ALMNA | |
| SCHEMBL9681926 | 0.86 | TBXA2R (0.87) | TBXA2RMEN1KMT2A | |
| SCHEMBL17380973 | 0.84 | POLB (0.58) | POLBAGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9683004 | 0.83 | TBXA2R (0.64) | TBXA2RAGTR1AGTR2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |