Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681793 | 0.94 | TBXA2R (0.67) | TBXA2RLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL9683131 | 0.93 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9683508 | 0.92 | TBXA2R (0.62) | TBXA2RLMNASMN1; SMN2NPSR1ALOX5AP | |
| SCHEMBL9682437 | 0.92 | TBXA2R (0.76) | TBXA2RLMNAMEN1KMT2AAGTR1 | |
| SCHEMBL9681897 | 0.91 | TBXA2R (0.78) | TBXA2RLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL9681443 | 0.89 | TBXA2R (0.61) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9681823 | 0.87 | TBXA2R (0.83) | TBXA2RLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL9683048 | 0.84 | MAPT (0.53) | TBXA2RLMNAMEN1KMT2AMAPT | |
| SCHEMBL9683004 | 0.83 | TBXA2R (0.64) | TBXA2RLMNAMAPTTP53AGTR1 | |
| SCHEMBL9699144 | 0.82 | TBXA2R (0.76) | TBXA2RALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |