Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Losartan SCHEMBL4222 | 0.87 | AGTR1 (0.86) | AGTR1AGTR2 | |
| Losartan SCHEMBL4677535 | 0.86 | AGTR1 (0.84) | AGTR1AGTR2 | |
| SCHEMBL459 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL20257387 | 0.83 | AGTR1 (0.81) | AGTR1AGTR2 | |
| Losartan SCHEMBL14169312 | 0.82 | AGTR1 (0.80) | AGTR1AGTR2 | |
| SCHEMBL29394324 | 0.82 | AGTR1 (0.89) | AGTR1AGTR2 | |
| SCHEMBL12786639 | 0.81 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL3633085 | 0.81 | AGTR1 (0.78) | AGTR1AGTR2 | |
| Losartan SCHEMBL2577425 | 0.81 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL306 | 0.80 | AGTR1 (0.76) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |