Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenolsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonic Acid SCHEMBL18275 | 0.97 | LMNA (1.00) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL29965481 | 0.97 | LMNA (1.00) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL10622999 | 0.97 | LMNA (1.00) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL2518117 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL687364 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL119166 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL20815893 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL125057 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL8781964 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL11084147 | 0.94 | LMNA (0.94) | LMNAALDH1A1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153348-A | Ester exchanging a choline salt with carbonate esters in aprotic solvents and solidification | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-10-06 | — | — | US | claimed |
| EP-0475512-A1 | Process for preparing quaternary ammonium carbonate esters | UNILEVER N.V. (NL) | 1992-03-18 | — | — | EP | claimed |