Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 10/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487413 | 0.84 | EED (0.47) | SLC6A4SLC6A2 | |
| SCHEMBL27504233 | 0.84 | EED (0.47) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL7955369 | 0.82 | EED (0.46) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL7946334 | 0.82 | EED (0.46) | SLC6A4SLC6A2 | |
| SCHEMBL14499009 | 0.79 | SCN4A (0.43) | SSTR4SCN4ASLC6A4LMNASCN1A | |
| SCHEMBL9683102 | 0.77 | ALDH1A1 (0.44) | SCN4ASLC6A4LMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL9683107 | 0.76 | ALDH1A1 (0.43) | SCN4ASLC6A4LMNASCN1ASCN5A | |
| SCHEMBL17277334 | 0.74 | SSTR4 (0.48) | SSTR4SLC6A4CYP3A4TSHRKCNH2 | |
| SCHEMBL3671560 | 0.73 | ALDH1A1 (0.65) | SCN4ASLC6A4LMNASCN1ASCN5A | |
| SCHEMBL21618371 | 0.72 | TDP1 (0.49) | SLC6A4KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |