Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9683107 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4ESCN4ALMNASCN1A | |
| Hydrochloric Acid SCHEMBL7960100 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MAOAKMT2AMEN1 | |
| SCHEMBL9682093 | 0.77 | SSTR4 (0.45) | ALDH1A1SCN4ALMNASCN1ASCN5A | |
| SCHEMBL9683909 | 0.76 | SLC6A4 (0.40) | ALDH1A1KDM4ESLC6A4KMT2A | |
| SCHEMBL7953469 | 0.75 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL7953471 | 0.75 | ALDH1A1 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9682487 | 0.75 | SLC6A4 (0.39) | ALDH1A1KDM4ELMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL7955381 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7955380 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7956973 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |