Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360511 | 0.72 | ADORA2A (0.46) | EGFRSRCKDRTEKADORA2A | |
| SCHEMBL5694141 | 0.68 | DYRK1A (0.47) | ALDH1A1KMT2ARAB9ATSHRL3MBTL1 | |
| SCHEMBL25230669 | 0.68 | ELANE (0.48) | ALDH1A1ADORA2AADORA1KMT2ARAB9A | |
| SCHEMBL4343213 | 0.67 | ADORA2A (0.60) | ALDH1A1EGFRSRCKDRTEK | |
| SCHEMBL12223673 | 0.65 | KMT2A (0.53) | ALDH1A1ADORA2AADORA1KMT2ARAB9A | |
| SCHEMBL5694058 | 0.65 | EGFR (0.42) | EGFRADORA2AADORA1KMT2ARAB9A | |
| SCHEMBL5694208 | 0.65 | CFTR (0.53) | EGFRADORA2AADORA1KMT2A | |
| SCHEMBL3477048 | 0.65 | KMT2A (0.77) | ALDH1A1DNMT3AKMT2ARAB9ATSHR | |
| SCHEMBL27589887 | 0.65 | FDPS (0.50) | ALDH1A1KMT2ARAB9ATSHRL3MBTL1 | |
| SCHEMBL946620 | 0.64 | ADORA2A (0.56) | EGFRSRCKDRTEKADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464638-A2 | Oligonucleotide analogues with terminal 3'-3' or 5'-5'-internucleotide linkages | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |