SCHEMBL3477048

SCHEMBL3477048

O=C(c1ccccc1)n1cnc2ccccc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.77
RAB9A P51151 4/20 0.67
HPGD P15428 3/20 0.67
ALDH1A1 P00352 3/20 0.67
NPC1 O15118 3/20 0.67
MAPT P10636 2/20 0.67
HSD17B10 Q99714 1/20 0.67
MEN1 O00255 3/20 0.66
SMN1; SMN2 Q16637 4/20 0.56
ASAH1 Q13510 2/20 0.55
DNMT3A Q9Y6K1 1/20 0.52
MGAM O43451 1/20 0.51
F2 P00734 1/20 0.51
AMY1A P0DUB6 1/20 0.51
GAA P10253 1/20 0.51
SI P14410 1/20 0.51
SLC9A1 P19634 1/20 0.51
MGAM2 Q2M2H8 1/20 0.51
LMNA P02545 1/20 0.51
STAT6 P42226 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13844515 0.88 KMT2A (0.75) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL857765 0.83 SMN1; SMN2 (0.61) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL31229358 0.82 KMT2A (0.55) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL5440622 0.81 KMT2A (0.54) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL11443588 0.81 KMT2A (0.60) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL250172 0.81 HTT (0.66) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL5872635 0.79 KMT2A (0.51) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL5872634 0.79 KMT2A (0.51) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL28212537 0.79 KMT2A (0.51) KMT2ARAB9AHPGDALDH1A1NPC1
SCHEMBL3471303 0.79 KMT2A (0.67) KMT2ARAB9AHPGDALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
US-4542394-A MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND RICOH COMPANY, LTD. (JP) 1985-09-17 US claimed
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-05-30 US disclosed
EP-4347544-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES Dow Technology Investments LLC (US) 2024-04-10 EP disclosed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117242047-A Process for the vapor phase hydrogenation of aldehydes 陶氏技术投资有限责任公司 2023-12-15 CN disclosed
WO-2022250790-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2022-12-01 WO disclosed
EP-2970074-B1 HYDROFORMYLATION PROVESS USING A HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT DOW TECHNOLOGY INVESTMENTS LLC (US) 2019-04-24 EP disclosed
CN-104045532-B Hydroformylation process 陶氏技术投资有限责任公司 2018-05-25 CN disclosed
WO-1995018206-A1 PEROXYACID BLEACH PRECURSOR PARTICLE COATED WITH A WATER SOLUBLE ORGANIC ACID IN PARTICULATE FORM THE PROCTER & GAMBLE COMPANY (US) 1995-07-06 WO disclosed
EP-0659876-A2 Detergent additive composition. THE PROCTER & GAMBLE COMPANY (US) 1995-06-28 EP disclosed
WO-1995012652-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-05-11 WO disclosed
WO-1995001416-A1 MACHINE DISHWASHING COMPOSITION CONTAINING OXYGEN BLEACH AND PARAFFIN OIL AND BENZOTRIAZOLE COMPOUND SILVER TARNISHING INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed
US-5001239-A Formation of reissert compound of benzoyl benzimidazole VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1991-03-19 US disclosed
US-5001239-A Formation of reissert compound of benzoyl benzimidazole VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1991-03-19 US disclosed
US-4542394-A MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND RICOH COMPANY, LTD. (JP) 1985-09-17 US disclosed
US-4420479-A 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES ELI LILLY AND COMPANY (US) 1983-12-13 US disclosed
EP-0091795-A1 Olefinic benzimidazoles ELI LILLY AND COMPANY (US) 1983-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES ADH1C, ADH5, ALDH2 KMT2A 191/4885RAB9A 2415/4885HPGD 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.