Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990373 | 0.89 | KMT2A (0.49) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL4598444 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL31124079 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL31124167 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL17914244 | 0.83 | KMT2A (0.46) | ESR1ESR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9680648 | 0.83 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL8968025 | 0.82 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL29426396 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL4204276 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL9681068 | 0.82 | MAOA (0.60) | KMT2AMEN1ALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |