Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72584 | 0.87 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3FFAR1MEN1 | |
| SCHEMBL10850371 | 0.86 | PDE9A (0.46) | PDE9ASLC6A4SLC6A2SLC6A3FFAR1 | |
| SCHEMBL20068830 | 0.85 | SLC6A4 (0.53) | PDE9ASLC6A4SLC6A2SLC6A3FFAR1 | |
| SCHEMBL10848810 | 0.83 | SLC6A4 (0.45) | PDE9ASLC6A4SLC6A2SLC6A3MGLL | |
| SCHEMBL10807365 | 0.82 | CYP2D6 (0.53) | PDE9ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9683067 | 0.82 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL10851128 | 0.81 | PDE9A (0.47) | PDE9ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10605768 | 0.79 | EPHX2 (0.48) | SLC6A4SLC6A2SLC6A3FFAR1ACACB | |
| SCHEMBL10850002 | 0.78 | SLC6A2 (0.48) | PDE9ASLC6A4SLC6A2SLC6A3MGLL | |
| SCHEMBL10854349 | 0.76 | CYP2D6 (0.46) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |