SCHEMBL9683067

SCHEMBL9683067

CC(c1ccccc1)N1CC(COc2cccc(C(F)(F)F)c2)C1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 17/20 0.59
GRM2 Q14416 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682477 0.82 PDE9A (0.49) FFAR1
SCHEMBL31381192 0.76 GRM2 (0.53) FFAR1GRM2
SCHEMBL22365289 0.76 FFAR1 (1.00) FFAR1
SCHEMBL17000323 0.76 FFAR1 (1.00) FFAR1
SCHEMBL2665473 0.75 KMT2A (0.56) FFAR1GRM2
SCHEMBL2299216 0.74 KMT2A (0.59) FFAR1GRM2
SCHEMBL9683868 0.74 SCN4A (0.46) FFAR1
SCHEMBL31381288 0.72 KDM4E (0.51) FFAR1GRM2
SCHEMBL22365314 0.72 FFAR1 (0.69) FFAR1
SCHEMBL22365398 0.72 FFAR1 (0.69) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130309-A Cardiovascular disorders A. H. ROBINS COMPANY, INCORPORATED (US) 1992-07-14 US claimed
US-5130309-A Cardiovascular disorders A. H. ROBINS COMPANY, INCORPORATED (US) 1992-07-14 US disclosed