Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26207253 | 0.83 | ACHE (0.47) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL14665045 | 0.83 | LMNA (0.55) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL1062535 | 0.83 | LMNA (0.55) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26622729 | 0.83 | ACHE (0.52) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26622653 | 0.83 | ACHE (0.52) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26207951 | 0.82 | ACHE (0.46) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26622898 | 0.81 | ACHE (0.51) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26206937 | 0.81 | ACHE (0.46) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26208188 | 0.80 | ACHE (0.47) | ACHEALDH1A1LMNATP53MAPT | |
| SCHEMBL26209794 | 0.80 | ACHE (0.46) | ACHEALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153318-A | Viricides for hepatitis and human t-cell leukemia/lymphoma viruses | BURROUGHS WELLCOME CO. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0421739-A1 | 3'-azido purine nucleoside | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-04-10 | — | — | EP | disclosed |