Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069409 | 0.86 | CCR3 (0.64) | GBA1SLC6A3CCR3ACHECYP2D6 | |
| SCHEMBL7465330 | 0.86 | CCR3 (0.64) | GBA1SLC6A3CCR3ACHECYP2D6 | |
| SCHEMBL843343 | 0.86 | CCR3 (0.64) | GBA1SLC6A3CCR3ACHECYP2D6 | |
| SCHEMBL3582865 | 0.82 | FUCA1 (0.63) | GBA1CCR3SIGMAR1CYP2D6 | |
| SCHEMBL22235803 | 0.82 | GBA1 (0.59) | GBA1SLC6A3CCR3SIGMAR1GAA | |
| SCHEMBL1918964 | 0.82 | CCR3 (0.73) | SLC6A3CCR3SIGMAR1ACHECYP2D6 | |
| SCHEMBL3884681 | 0.81 | HRH3 (0.56) | GBA1SIGMAR1PYGLOPRM1OPRD1 | |
| SCHEMBL11227003 | 0.81 | GBA1 (0.61) | GBA1SLC6A3CCR3SIGMAR1GAA | |
| SCHEMBL7003079 | 0.80 | SLC6A3 (0.61) | GBA1SLC6A3CCR3SIGMAR1ACHE | |
| SCHEMBL7168199 | 0.80 | GBA1 (0.83) | GBA1SLC6A3SIGMAR1GAAPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |
| CN-86102422-A | The method for preparing azetidine derivatives | — | 1987-01-28 | — | — | CN | disclosed |