Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.65 |
| ▸ | MDM4 | O15151 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317646 | 0.85 | KCNMA1 (0.76) | KCNMA1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8820818 | 0.83 | MAPT (0.71) | KCNMA1TP53MAPTNPC1RAB9A | |
| SCHEMBL11331448 | 0.82 | KCNMA1 (0.77) | KCNMA1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27912234 | 0.82 | KCNMA1 (0.67) | KCNMA1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29175040 | 0.81 | SMN1; SMN2 (0.66) | KCNMA1TP53MAPTNPC1RAB9A | |
| SCHEMBL11834604 | 0.81 | MEN1 (0.85) | KCNMA1MAPTMEN1KMT2AGFER | |
| SCHEMBL22384783 | 0.81 | HDAC1 (0.68) | KCNMA1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28197181 | 0.81 | RAB9A (0.70) | KCNMA1TP53MAPTNPC1RAB9A | |
| SCHEMBL28652032 | 0.80 | KCNMA1 (0.60) | KCNMA1TP53MAPTNPC1RAB9A | |
| SCHEMBL5310996 | 0.80 | KCNMA1 (0.73) | KCNMA1TP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495626-A1 | Process for the preparation of tetrazole derivatives | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | disclosed |