Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683402 | 0.88 | ALDH1A1 (0.56) | GAALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9219757 | 0.88 | TP53 (0.63) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9216793 | 0.87 | POLB (0.58) | GAALMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9430659 | 0.86 | POLB (0.60) | GAALMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9221106 | 0.86 | POLB (0.60) | GAALMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9219577 | 0.84 | ALDH1A1 (0.52) | GAALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9682551 | 0.84 | ALDH1A1 (0.57) | GAALMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9430836 | 0.83 | TP53 (0.56) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9218097 | 0.82 | ALDH1A1 (0.62) | LMNAALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL9212362 | 0.82 | TP53 (0.52) | LMNAALDH1A1KDM4ENPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |