Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455991 | 0.77 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL9449230 | 0.76 | MAPT (0.50) | ELANEHCAR2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9681865 | 0.74 | C1R (0.39) | C1RHDAC6ELANEKDM4EHCRTR1 | |
| SCHEMBL9682726 | 0.73 | RAB9A (0.39) | ELANEHCAR2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9846095 | 0.65 | MAPT (0.50) | ELANEKDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL6902562 | 0.64 | MAPT (0.46) | ELANEKDM4EHCRTR1MAPTSMN1; SMN2 | |
| SCHEMBL14583311 | 0.64 | ELANE (0.51) | ELANEMAPTSMN1; SMN2RAB9APPARG | |
| SCHEMBL5674725 | 0.64 | PPARG (0.50) | HDAC6HCRTR1HCRTR2MAPTRAB9A | |
| SCHEMBL11330961 | 0.63 | MAPT (0.48) | KDM4EHCRTR1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9846186 | 0.63 | MAPT (0.48) | ELANEHCAR2KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |