Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268706 | 0.74 | RAB9A (0.48) | MAPTELANEKDM4ENPC1RAB9A | |
| SCHEMBL9682722 | 0.74 | C1R (0.39) | C1RMAPTPPARGELANEPPARD | |
| SCHEMBL9681875 | 0.72 | MAPT (0.37) | MAPTELANEKDM4ENPC1ALDH1A1 | |
| SCHEMBL6805005 | 0.68 | PPARG (0.44) | MAPTPPARGELANENPC1ALDH1A1 | |
| SCHEMBL25774152 | 0.65 | PPARG (0.45) | MAPTPPARGELANEPPARAHCRTR1 | |
| SCHEMBL9846349 | 0.65 | MAPT (0.50) | MAPTELANEKDM4ENPC1RAB9A | |
| SCHEMBL2543163 | 0.64 | PPARG (0.51) | MAPTPPARGELANEPPARDPPARA | |
| SCHEMBL2543168 | 0.64 | PPARG (0.51) | MAPTPPARGELANEPPARDPPARA | |
| SCHEMBL6902562 | 0.64 | MAPT (0.46) | MAPTPPARGELANEHCRTR1KDM4E | |
| SCHEMBL8716001 | 0.64 | ELANE (0.51) | MAPTPPARGELANENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |