Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076263 | 0.81 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL2818996 | 0.80 | PDE10A (0.49) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL38662586 | 0.79 | MEN1 (0.71) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL2443270 | 0.79 | MEN1 (0.71) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL829508 | 0.72 | TSHR (0.56) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL13134232 | 0.72 | PDE10A (0.47) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL31026536 | 0.72 | MAOA (0.52) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL12220557 | 0.72 | HSD17B10 (0.62) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL642681 | 0.72 | MAOA (0.52) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL29377848 | 0.72 | PDE10A (0.66) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0360443-A1 | Acridine compound and photopolymerizable composition using the same | Hitachi Chemical Co., Ltd. (JP) | 1990-03-28 | — | — | EP | disclosed |