Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365849 | 0.91 | NPSR1 (0.65) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9545929 | 0.86 | NPSR1 (0.72) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL2976362 | 0.86 | ALDH1A1 (0.85) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9221970 | 0.84 | ALDH1A1 (0.62) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9693631 | 0.84 | NPSR1 (0.62) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL7851367 | 0.84 | NPSR1 (0.69) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL7870110 | 0.84 | NPSR1 (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL3886220 | 0.83 | NPSR1 (0.67) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9377431 | 0.82 | NPSR1 (0.66) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 | |
| SCHEMBL10366538 | 0.82 | ALDH1A1 (0.77) | CYP1A2CYP2C9CYP2C19CYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223406-B1 | PYRIMIDINE DERIVATIVES AND HERBICIDAL USES THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-08-29 | — | — | EP | claimed |
| US-4770691-A | HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-13 | — | — | US | claimed |
| EP-0223406-A1 | Pyrimidine derivatives and herbicidal uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-05-27 | — | — | EP | claimed |
| US-5149357-A | Herbicidal substituted benzoylsulfonamides | FMC CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0223406-B1 | PYRIMIDINE DERIVATIVES AND HERBICIDAL USES THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4770691-A | HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0223406-A1 | Pyrimidine derivatives and herbicidal uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |