SCHEMBL2976362

SCHEMBL2976362

COC(=O)c1ccccc1Oc1nc(OC)cc(OC)n1

nearest known ligand 0.85

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.85
SMN1; SMN2 Q16637 1/20 0.85
NPSR1 Q6W5P4 2/20 0.72
CYP1A2 P05177 3/20 0.70
CYP2C9 P11712 3/20 0.70
CYP2C19 P33261 3/20 0.70
CYP3A4 P08684 2/20 0.70
ATM Q13315 1/20 0.69
GAA P10253 1/20 0.67
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10366070 0.92 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL10366538 0.92 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL9545929 0.91 NPSR1 (0.72) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL10368177 0.91 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL7851367 0.89 NPSR1 (0.69) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL3886220 0.88 NPSR1 (0.67) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL4318924 0.88 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL9384288 0.86 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL9377431 0.86 NPSR1 (0.66) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9
SCHEMBL9683012 0.86 CYP1A2 (0.68) ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-20060009359-A1 Selective heteroaryloxy-acetamide-based herbicides FEUCHT DIETER 2006-01-12 US claimed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US claimed
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 US claimed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
US-20040116294-A1 Herbicides based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2004-06-17 US claimed
US-20040102321-A1 Selective heteroaryloxy- acetamides-based herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-05-27 US claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
EP-0223406-B1 PYRIMIDINE DERIVATIVES AND HERBICIDAL USES THEREOF KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-08-29 EP claimed
US-4770691-A HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-13 US claimed
EP-0223406-A1 Pyrimidine derivatives and herbicidal uses thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-05-27 EP claimed
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO., LTD. (KR) 2019-02-19 US disclosed
EP-2836072-B1 HERBICIDAL COMPOSITION COMPRISING AN URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO LTD (KR) 2018-11-21 EP disclosed
US-4770691-A HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed
EP-0223406-A1 Pyrimidine derivatives and herbicidal uses thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009359-A1 Selective heteroaryloxy-acetamide-based herbicides AADAC, HACL2, HDHD5 ALDH1A1 565/4885SMN1; SMN2 3648/4885NPSR1 3055/4885
US-20040102321-A1 Selective heteroaryloxy- acetamides-based herbicides AADAC, HACL2, HDHD5 ALDH1A1 677/4885SMN1; SMN2 3612/4885NPSR1 3069/4885
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones DDT, CBR3, CYP1B1 ALDH1A1 148/4885SMN1; SMN2 3929/4885NPSR1 1839/4885
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT ALDH1A1 591/4885SMN1; SMN2 3410/4885NPSR1 2385/4885
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides AADAC, NOTUM, NAAA ALDH1A1 95/4885SMN1; SMN2 4268/4885NPSR1 1014/4885
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 ALDH1A1 474/4885SMN1; SMN2 3221/4885NPSR1 4679/4885
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 ALDH1A1 108/4885SMN1; SMN2 3842/4885NPSR1 1734/4885
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one DDT, TARS2, CBR3 ALDH1A1 284/4885SMN1; SMN2 3715/4885NPSR1 3617/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC ALDH1A1 322/4885SMN1; SMN2 3395/4885NPSR1 2810/4885
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient UNG, DDT, HDHD5 ALDH1A1 474/4885SMN1; SMN2 3221/4885NPSR1 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.