Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683040 | 0.90 | ERCC5 (0.41) | ERCC5FEN1SHBGKMT2AMEN1 | |
| SCHEMBL9683047 | 0.90 | ERCC5 (0.41) | ERCC5FEN1SHBGKMT2AMEN1 | |
| SCHEMBL9681239 | 0.83 | NPC1 (0.46) | KMT2AMEN1RAB9ALMNATSHR | |
| SCHEMBL5997915 | 0.80 | HPGD (0.41) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL8179369 | 0.78 | HPGD (0.49) | RAB9ALMNATSHRKDM4ENPC1 | |
| SCHEMBL27519602 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1LMNATSHRKDM4E | |
| SCHEMBL8035923 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1LMNATSHRKDM4E | |
| SCHEMBL9267454 | 0.77 | HDAC3 (0.42) | KMT2ALMNAHPGDALDH1A1MAPK8 | |
| SCHEMBL5669568 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1LMNATSHRKDM4E | |
| SCHEMBL9021316 | 0.77 | HDAC3 (0.42) | KMT2ALMNAHPGDALDH1A1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147892-A | BENZYL KETONES AND FUNGICIDES CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-15 | — | — | US | disclosed |