Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838547 | 0.81 | CYP3A4 (0.39) | CYP3A4NPSR1 | |
| SCHEMBL28662 | 0.70 | CYP3A4 (1.00) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL713076 | 0.65 | CYP3A4 (0.76) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL18368139 | 0.64 | CYP3A4 (0.84) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL10799429 | 0.64 | CYP3A4 (0.84) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL18194710 | 0.62 | CYP3A4 (0.80) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL157928 | 0.62 | CYP3A4 (0.71) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL10997976 | 0.61 | CYP3A4 (0.79) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL24669059 | 0.61 | CYP3A4 (0.76) | CYP3A4NPSR1ADORA2BADORA2AKMT2A | |
| SCHEMBL13775112 | 0.61 | CYP3A4 (0.68) | CYP3A4NPSR1ADORA2BADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162417-A | Crosslinked Polyvinylpyrrolidone | ISP INVESTMENTS INC. (US) | 1992-11-10 | — | — | US | claimed |