Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683748 | 0.91 | CFTR (0.42) | TDP1CFTRVCAM1S1PR4TSHR | |
| SCHEMBL9685075 | 0.83 | TDP1 (0.38) | TDP1VCAM1S1PR4TSHRCYP3A4 | |
| SCHEMBL10532607 | 0.69 | MAPT (0.44) | TDP1TSHRCYP3A4ALDH1A1MEN1 | |
| SCHEMBL3309493 | 0.68 | TDP1 (0.47) | TDP1VCAM1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL9683053 | 0.68 | HSD17B10 (0.42) | VCAM1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9546820 | 0.67 | ALDH1A1 (0.39) | TDP1CFTRTSHRCYP3A4ALDH1A1 | |
| SCHEMBL4864448 | 0.66 | TDP1 (0.57) | TDP1VCAM1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL27751205 | 0.65 | TDP1 (0.52) | TDP1VCAM1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL8628490 | 0.65 | MAPT (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30256667 | 0.65 | TDP1 (0.67) | TDP1VCAM1TSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162583-A | Triazole Herbicide Intermediates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-10 | — | — | US | claimed |