Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 5/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683067 | 0.74 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL9682608 | 0.73 | CYP2D6 (0.45) | CYP2D6FFAR1LMNASCN5ASCN9A | |
| SCHEMBL9683102 | 0.73 | ALDH1A1 (0.44) | SCN4ASCN8ACYP2D6LMNASCN1A | |
| SCHEMBL9683895 | 0.72 | CYP2D6 (0.55) | CYP2D6LMNAMC4RALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9683107 | 0.72 | ALDH1A1 (0.43) | SCN4ASCN8ACYP2D6LMNASCN1A | |
| SCHEMBL9682093 | 0.71 | SSTR4 (0.45) | SCN4ASCN8ACYP2D6LMNASCN1A | |
| SCHEMBL2921816 | 0.70 | CYP2D6 (0.61) | CYP2D6MC4RALDH1A1 | |
| SCHEMBL2920210 | 0.70 | CYP2D6 (0.61) | CYP2D6MC4RALDH1A1 | |
| SCHEMBL9682612 | 0.70 | CYP2D6 (0.52) | CYP2D6LMNAMC4RALDH1A1MAPT | |
| SCHEMBL6097455 | 0.69 | CYP2D6 (0.65) | CYP2D6MC4RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |