Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194871 | 0.91 | CYP1A2 (0.55) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL395803 | 0.89 | ALDH1A1 (0.59) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL9681942 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL15453519 | 0.82 | TSHR (0.45) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL11560910 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL9683081 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL6583167 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL3819838 | 0.74 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL4691068 | 0.74 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL337085 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP1A2TSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |