Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19514763 | 0.91 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11560910 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHR | |
| SCHEMBL9683074 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL17233403 | 0.75 | TSHR (0.46) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL15453370 | 0.74 | MGAM (0.48) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10770064 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9015163 | 0.73 | CYP2C19 (0.53) | ALDH1A1TSHR | |
| SCHEMBL10770138 | 0.71 | CYP2C19 (0.34) | ALDH1A1TSHR | |
| SCHEMBL15460034 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL19293682 | 0.70 | MGAM (0.38) | ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |