Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815183 | 0.97 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL9601098 | 0.89 | ADRA2A (0.50) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11785899 | 0.89 | DGKA (0.73) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL5319219 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL28705899 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL14760960 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL11794989 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL9948675 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL10430876 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL28686429 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| CN-101611762-B | Compound quick-action inhibitor against generation of methane and preparation method and application thereof | CHINA AGRICULTURAL UNIVERSITY (CN) | 2011-12-28 | — | — | CN | disclosed |
| CN-101611762-A | A kind of compound quick-action inhibitor against generation of methane and its production and use | UNIV CHINA AGRICULTURAL | 2009-12-30 | — | — | CN | disclosed |
| US-5147791-A | Reacting diester and dialcohol in presence of enzyme catalyst;enantiomorphs | UNIVERSITY OF NEW MEXICO (US) | 1992-09-15 | — | — | US | disclosed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-3971757-A | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3966711-A | 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |