Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107257 | 1.00 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL9725832 | 0.87 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL11392282 | 0.85 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10209754 | 0.78 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL14388207 | 0.77 | AOC3 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL2736648 | 0.77 | KDM4E (0.57) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL10255083 | 0.77 | AOC3 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL359794 | 0.77 | KDM4E (0.57) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL4186259 | 0.77 | KDM4E (0.57) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL4828396 | 0.77 | AOC3 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132457-A | Stereospecific synthesis of 2(R)-2-methyl-3-dimethylamino-propiophenone (d-DAMP) | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1992-07-21 | — | — | US | disclosed |