Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107257 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL9683219 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL12570043 | 0.74 | KDM4E (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL12512543 | 0.74 | KDM4E (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL12512553 | 0.74 | KDM4E (0.58) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL10209754 | 0.74 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL11392282 | 0.73 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL13487978 | 0.73 | LMNA (0.54) | SLC6A2SLC6A4SLC6A3HTR2AKDM4E | |
| SCHEMBL804251 | 0.72 | AOC3 (0.70) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL907809 | 0.72 | AOC3 (0.70) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4226948-A | — | — | None | — | — | JP | disclosed |
| JP-H04226948-A | CHIRAL SYNTHESIS OF 1-ARYL-3-AMINOPROPANE-1-OL | ELI LILLY & CO | 1992-08-17 | — | — | JP | disclosed |