Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681363 | 0.87 | MAPT (0.55) | MAPTL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL14857961 | 0.79 | MAPT (0.43) | MAPTL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL9701292 | 0.79 | MAPT (0.74) | MAPTL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL9681851 | 0.79 | RAB9A (0.51) | MAPTKMT2AMEN1RAB9ACYP1A2 | |
| SCHEMBL31237109 | 0.73 | MAPT (0.53) | MAPTL3MBTL1KMT2AMEN1RECQL | |
| SCHEMBL11641120 | 0.72 | MEN1 (0.58) | MAPTL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL6832051 | 0.72 | POLB (0.50) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL16563651 | 0.70 | MAPT (0.48) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9680964 | 0.70 | MAPT (0.42) | MAPTKMT2AMEN1RAB9ACYP1A2 | |
| SCHEMBL7832980 | 0.69 | NPC1 (0.70) | MAPTL3MBTL1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |