SCHEMBL9683412

SCHEMBL9683412

Cc1ccccc1S(=O)(=O)N(C)c1cccc(N(C)c2ccc(N(C)c3ccccc3)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCOLN3 Q8TDD5 1/20 0.49
PKM P14618 2/20 0.46
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
NR3C2 P08235 1/20 0.42
PGR P06401 1/20 0.42
HTT P42858 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.40
NR1H3 Q13133 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822613 0.84 MCOLN3 (0.60) MCOLN3PKMKDM4EGLACA12
Hydrochloric Acid SCHEMBL5808143 0.82 MCOLN3 (0.58) MCOLN3PKMKDM4EGLACA12
SCHEMBL9683418 0.79 CA12 (0.71) MCOLN3CA12CA9HTTNPSR1
SCHEMBL9480275 0.77 ALDH1A1 (0.52) NR3C2ALDH1A1TP53MAPT
SCHEMBL8351509 0.76 MCOLN3 (0.64) MCOLN3PKMKDM4EGLACA12
SCHEMBL9683388 0.76 MEN1 (0.49) NR3C2PGRALDH1A1
Hydrochloric Acid SCHEMBL5804305 0.75 MCOLN3 (0.62) MCOLN3PKMKDM4EGLACA12
SCHEMBL12258323 0.73 CHKA (0.50) NR3C2HTTNPSR1ALDH1A1TSHR
SCHEMBL3706061 0.72 PKM (0.50) MCOLN3PKMKDM4ECA12CA9
SCHEMBL9479922 0.72 POLB (0.55) NR3C2PGRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed